Analysis Note

ControlExpressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells

Application

Development of IRMA assays for ET-1 (CBL 85) and ET-3 (CBL 86)

Suitable for immunocytochemistry on frozen sections

Optimal working dilutions must be determined by the end user.

Research CategoryNeuroscience

This Anti-Endothelin Antibody, C-terminus, clone 3G10 is validated for use in IC for the detection of Endothelin.

Research Sub CategoryCNS Control of MetabolismHormones & Receptors

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Epitope: C-terminus

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Protein A purified

Format: Purified

The monoclonal is presented at in phosphate buffered saline containing 10mM sodium azide. We recommend that each laboratory determine an optimum working titre for use in its particular application.

Specificity

Recognizes the C-terminal region of all endothelins (amino acid residues 15-21) when used as a capture antibody in IRMA assays. The antibody does not cross-react with "big" endothelin.

Storage and Stability

For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.